(Report from Brittish National Health Service, Tavistock 2019. No eviden´ce for positive effects of puberty blockers for girls. On the contrary, suicidal ideasation, dysphosira, self-mutliation orsened).
(Transsexuals with hormone treatment 2-3 times more likely dvelop stroke. Confirms earlier conclusion from Nat.Ist.Health, NIH,USA)
Nienke M. Nota , Chantal M. Wiepjes , Christel J.M. de Blok , Louis J.G. Gooren , Baudewijntje P.C. Kreukels , Martin den Heijer
"Occurrence of Acute Cardiovascular Events in Transgender Individuals Receiving Hormone Therapy
Results From a Large Cohort Study". Circulation. 2019. 139:1461–1462
Getahun D, Nash R, et al. "Cross-sex Hormones and Acute Cardiovascular Events in Transgender Persons: A Cohort Study". Ann Intern Med. 2018. 169:205-213.
(Memory impairent with puberty blockers)
Schneider MA, Spritzer PM, Soll BMB, Fontanari AMV, Carneiro M, Tovar-Moll F, Costa AB, da Silva DC, Schwarz K,, Anes M, Tramontina S, Lobato MIR. "Brain Maturation, Cognition and Voice Pattern in a Gender Dysphoria Case under Pubertal Suppression". Front Hum Neurosci. 2017. 11:528.
Mul D, Versluis-den Bieman HJ, Slijper FM, Oostdijk W, Waelkens JJ, Drop SL. "Psychological assessments before and after treatment of early puberty in adopted children". Acta Paediatr. 2001. 90:965-71.
(Press Release, Endochrinologists warn for side-effects from puberty blockers and Hormones).
Ladilaw MK et al. "Endocrinologists Warn of Grave Dangers, Sterility Caused by Puberty Blockers and Hormones for Child and Adolescent Gender Dysphoria Jan 2019
Chew D, Anderson J, Williams K, et al. "Hormonal Treatment in Young People With Gender Dysphoria: A Systematic Review. Pediatrics". 2018. 141(4):e20173742
(Literature review. Conclusion "..protocol is founded upon an unscientific gender ideology, lacks an evidence base, and violates the long-standing ethical principle of “First do no harm.”)
"Gender Dysphoria in Children. American College of Pediatricians". nov 2018
(The percentages denote how many gender dysphoric patints that show psychiatric promlems. MtF=Male-to-Female, FtM = Female-to-Male).
(This recent study show that also for girls there is a very high "comorbidity".This has changed to the orse in the past 10 years).
75%. MtF & FtM, Kaltiala-Heino R, Sumia M, Työläjärvi M, Lindberg N. "Two years of gender identity service for minors: overrepresentation of natal girls with severe problems in adolescent development". Child Adolesc Psychiatry Ment Health. 2015 Apr 9;9:9. doi: 10.1186/s13034-015-0042-y. eCollection 2015.
Goddard JC, Vickery RM, Qureshi A, Summerton DJ, Khoosal D, Terry TR. "Feminizing genitoplasty in adult transsexuals: early and long-term surgical results". BJU Int. 2007;100:607-613. reassignment surgery (30).
Löwenberg H, Lax H, Neto RR, Krege S. "Complications, subjective satisfaction and sexual experience by gender reassignment surgery in male-to-female transsexual". Z Sexualforsch. 2010;23:328-347.
46.9% MtF, (Citation from the article: "The authors of the study stress the great importance of including personality assessment in standard GID diagnostic procedures, as presence or absence of psychiatric disease comorbidity is one of the contributing factors to the successful or unsuccessful SRS outcome" ).
Hess J. et al. "It is also possible that the positive results of our survey represent patients’ wish for social desirability rather than the real situation". Dtsch Arztebl Int. 2014 Nov; 111(47): 795-801.
66.6% MtF, 46% FtM.
Duišin D, Batinić B, Barišić J, Djordjevic ML, Vujović S, Bizic M."Personality disorders in persons with gender identity disorder."
ScientificWorldJournal. 2014;2014:809058. doi: 10.1155/2014/809058. Epub 2014 May 13.
77% MtF, 23% FtM.
Madeddu F, Prunas A, Hartmann D. "Prevalence of axis II disorders in a sample of clients undertaking psychiatric evaluation for sex reassignment surgery". Psychiatric Quarterly. 2009. 80:261-267
Joel D, Berman Z, Tavor I, Wexler N, Gaber O, Stein Y, Shefi N, Pool J, Urchs S, Margulies DS, Liem F, Hänggi J, Jäncke L, Assaf Y. "Sex beyond the genitalia: The human brain mosaic". Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15468-73.
New Scientist "Scans prove there's no such thing as a 'male' or 'female' brain"
(Claims that there are differnces in male and female brain structures are wrong)
Jäncke L1, Mérillat S, Liem F, Hänggi J. "Brain size, sex, and the aging brain". Hum Brain Mapp. 2015 Jan;36(1):150-69.
("Around 35% of referred young people present with moderate to severe autistic traits". A British Medical Journals Journal)
Butler G, De Graaf N, Wren B, Carmichael P. Assessment and support of children and adolescents with gender dysphoria. Arch Dis Child 2018 https://adc.bmj.com/content/early/2018/04/26/archdischild-2018-314992 (accessed 22 may 2019)
(Many references in his review, one of the foremost research centres for transsexualism, gender incongrunce).
van der Miesen AIR, de Vries ALC, Steensma TD, Hartman CA. "Autistic Symptoms in Children and Adolescents with Gender Dysphoria". J Autism Dev Disord. 2018. 48:1537-1548
Strang JF, Powers MD, Knauss M, Sibarium E, Leibowitz SF, Kenworthy L, Sadikova E, Wyss S, Willing L, Caplan R, Pervez N, Nowak J, Gohari D, Gomez-Lobo V, Call D, Anthony LG. "They Thought It Was an Obsession: Trajectories and Perspectives of Autistic Transgender and Gender-Diverse Adolescents". J Autism Dev Disord. 2018;48:4039-4055.
(US Survey, More than 27,000 respondrs. 11% MtF officially detransitioned, regretters likely manyfold more. x5 higher than what ANOVA/ Karolinska report).
Quora: How common is it for transgender people to regret their gender transition, possibly to the point of transitioning back?
Summary of the US Survey:
(UK NHS, Tavistock: 9,5% "openly" regret. Adolescents that developed dysphoria).
Churcher Clarke, A., Spiliadis, A. ‘Taking the lid off the box’: The value of extended clinical assessment for adolescents presenting with gender identity difficulties. 2019.
(The strong assertion/conclusion from Endocrinological Society in their International Guidelines. The paper is authored by many of the internationally recognized most eperienced and active centres in research and treatment of transsexualism /gender incongruence).
Wylie C Hembree Peggy T Cohen-Kettenis Louis Gooren Sabine E Hannema Walter J Meyer M Hassan Murad Stephen M Rosenthal Joshua D Safer Vin Tangpricha Guy G T’Sjoen.
"Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society Clinical Practice Guideline". The Journal of Clinical Endocrinology & Metabolism, 102: 3869–3903,